What is Profound treatment?
Profound is a minimally invasive bipolar RF system with patented Real Time Temperature Control that utilizes 5 pairs of micro-needle electrodes, deployed into the dermis, to precisely deliver fractionated thermal injuries in the deep reticular dermis, where the concentration of collagen is the highest. Fractionated thermal zones are created within the dermis, without thermal impact to the epidermis. Thermal injury to treated areas stimulates would healing, dermal remodeling and new elastin, collagen, and hyaluronic acid formation, resulting in visible skin improvement.
Why is Profound a unique, novel device for treating skin laxity and increasing dermal volume, particularly of the jawline and submental area?
The Profound system incorporates temperature sensors embedded within the micro-needles and a realtime temperature feedback algorithm to reach and maintain an optical dermal temperature of 67°C for 3-4 seconds, regardless of skin impedance or thermal conditions. Only Profound’s temperature-based feedback algorithm can predictably meet the desired thermal endpoint. With this unique approach, a vigorous wound healing response is initiated with a profound increase in elastin and collagen observed at 10 weeks after treatment; thereby, resulting in greater clinical efficacy for rhytide and skin laxity treatment.
What is the effect of temperature on the dermal remodeling process?
To be effective, non-surgical skin rejuvenation procedures need to trigger the dermal remodeling process, so that a global wound healing response is triggered and new elastin and collagen will proliferate. Loss of elastin and collagen due to genetics and aging results in skin laxity and loss of elasticity. It is known from the literature that partially denaturizing collagen is much more effective at triggering neocollagenesis than fully denatured collagen.1,2 Partially denatured collagen can heal 38% faster than fully denatured collagen and produces a more profound wound healing response. Dosimetry studies have shown that to consistently produce partially denatured collagen, it is important to reach and maintain a target dermal temperature at an optimal range of 67°C – 74°C for 3-4 seconds. Only with Profound is it possible to accurately reach and maintain the exact thermal dose of energy (temperature and time at temperature) needed to partially denature collagen and create the fastest healing response for dermal remodeling.